Percodan contains a combination of aspirin and oxycodone. Aspirin belongs to a group of drugs called salicylates. It works by reducing substances in the body that cause pain, fever, and inflammation. Oxycodone is an opioid pain medication. An opioid is sometimes called a narcotic.
Percodan is used to relieve moderate to severe pain.
Percodan may also be used for purposes not listed in this medication guide.
Oxycodone can slow or stop your breathing. Never take Percodan in larger amounts, or for longer than prescribed.
Oxycodone may be habit-forming, even at regular doses. Take Percodan exactly as prescribed by your doctor. Never share the medicine with another person. MISUSE OF NARCOTIC PAIN MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.
Aspirin should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox. Aspirin can cause a serious and sometimes fatal condition called Reye’s syndrome in children.
You should not take Percodan if you have a bleeding disorder, a recent history of stomach or intestinal bleeding, if you take a blood thinner, or if you are allergic to aspirin, oxycodone, or an NSAID (non-steroidal anti-inflammatory drug) such as Advil, Aleve, Naprosyn, Cataflam, Celecoxib, Feldene, Indocin, Mobic, Toradol, Voltaren, and others. Do not use Percodan if you have used a MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.
Percodan Before taking this medicine
You should not take Percodan if you are allergic to aspirin or oxycodone, or if you have:
- a bleeding or blood clotting disorder such as hemophilia;
- ulcer or obstruction in the stomach;
- severe asthma or breathing problems;
- an allergy to an NSAID (nonsteroidal anti-inflammatory drug) such as Advil, Aleve, Motrin, Naprosyn, Orudis, Cataflam, Celecoxib, Feldene, Indocin, Lodine, Mobic, Relafen, Toradol, Voltaren, and others; or
- if you are taking a blood thinner such as warfarin (Coumadin, Jantoven).
Do not use Percodan if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
Do not give this medication to a child or teenager with a fever, flu symptoms, or chicken pox. Aspirin can cause Reye’s syndrome, a serious and sometimes fatal condition in children.
Some medicines can interact with oxycodone and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take medicine for depression, mental illness, Parkinson’s disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.